Poor diuretic response associated with worse clinical outcomes

Poor diuretic response is associated with worse in-hospital and post-discharge clinical outcomes, results of the a trial reveal. The study also found that serelaxin has a neutral effect on diuretic response. The trial was a double blind, placebo-controlled trial of 1161 patients admitted to hospital with acute heart failure. Patients were randomized to receive 48-hour infusions of placebo or serelaxin (30µg/kg per day) within 16 hours from presentation. Primary analysis of the study showed that...